More on vitamin C deficiency in mice and humans

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Combined vitamin C and vitamin E deficiency worsens early atherosclerosis in apolipoprotein E-deficient mice.

OBJECTIVE To assess the role of combined deficiencies of vitamins C and E on the earliest stages of atherosclerosis (an inflammatory condition associated with oxidative stress), 4 combinations of vitamin supplementation (low C/low E, low C/high E, high C/low E, and high C/high E) were studied in atherosclerosis-prone apolipoprotein E-deficient mice also unable to synthesize their own vitamin C ...

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Vitamin C deficiency fails to protect mice from malaria.

Nutritional deficiencies are frequent in malaria-endemic areas. It seems that micronutrient antioxidants play an important role in malaria parasite's proliferation. Thus, the effect of vitamin C deficiency on malaria infection was examined in mice. When vitamin C deficient mice, L-gulono-gamma-lactone oxidase gene knockout mice which are unable to synthesize ascorbic acid, were infected with a ...

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Vitamin D deficiency and stroke

Vitamin D comprises a group of fat-soluble pro-hormones, obtained from sun exposure, food, and supplements, and it must undergo two hydroxylation reactions to be activated in the body. Several studies have shown the role of vitamin D in mineral metabolism regulation, especially calcium, phosphorus, and bone metabolism. Some factors such as inadequate vitamin intake and liver or kidney disorders...

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Deficiency of Vitamin C in South Asia

Vitamin C (L-ascorbic acid) is a water soluble vitamin which is an antioxidant and has a wide variety of biological functions for growth and development of the human body. It is essential for maintaining good health. The objective of this review is to share with the scientific community, the status of vitamin C in the South Asian populations compared to other populations in the world. The focus...

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ژورنال

عنوان ژورنال: Hepatology

سال: 2011

ISSN: 0270-9139

DOI: 10.1002/hep.24296